Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484858 | 1.00 | GABRA1 (0.32) | GABRA1LMNAHTT | |
| SCHEMBL24484957 | 0.95 | BTK (0.32) | LMNA | |
| SCHEMBL29630025 | 0.95 | BTK (0.32) | LMNA | |
| SCHEMBL29629942 | 0.94 | — | — | |
| SCHEMBL24484862 | 0.94 | — | — | |
| SCHEMBL24485702 | 0.86 | BTK (0.33) | GABRA1LMNA | |
| SCHEMBL29629890 | 0.86 | BTK (0.33) | GABRA1LMNA | |
| SCHEMBL24485042 | 0.84 | F11 (0.32) | GABRA1LMNAHTT | |
| SCHEMBL29629967 | 0.84 | F11 (0.32) | GABRA1LMNAHTT | |
| SCHEMBL29630230 | 0.84 | ANO1 (0.33) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251616-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven (BE) | 2023-10-04 | — | — | EP | claimed |
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | claimed |
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |