Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29095735 | 1.00 | MAPT (0.44) | MAPTTSHRALOX15HSD17B10TDP2 | |
| SCHEMBL29630244 | 0.91 | TDP2 (0.44) | MAPTTSHRALOX15HSD17B10TDP2 | |
| SCHEMBL29095783 | 0.91 | TDP2 (0.44) | MAPTTSHRALOX15HSD17B10TDP2 | |
| SCHEMBL24484502 | 0.90 | TDP2 (0.43) | MAPTTSHRTDP2PTGS2TP53 | |
| SCHEMBL29630286 | 0.90 | TDP2 (0.43) | MAPTTSHRTDP2PTGS2TP53 | |
| SCHEMBL24485224 | 0.86 | TDP2 (0.42) | MAPTTSHRALOX15TDP2PTGS2 | |
| SCHEMBL24485054 | 0.81 | PTGS2 (0.48) | MAPTTSHRPTGS2LMNAALDH1A1 | |
| SCHEMBL24484498 | 0.81 | PTGS2 (0.47) | MAPTTSHRPTGS2LMNAALDH1A1 | |
| SCHEMBL29630207 | 0.81 | PTGS2 (0.47) | MAPTTSHRPTGS2LMNAALDH1A1 | |
| SCHEMBL29630215 | 0.80 | PTGS2 (0.61) | MAPTTSHRPTGS2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |