Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484502 | 1.00 | TDP2 (0.43) | TDP2MRGPRX4PTGS2TP53TSHR | |
| SCHEMBL29630244 | 0.91 | TDP2 (0.44) | TDP2MRGPRX4PTGS2TP53TSHR | |
| SCHEMBL29095783 | 0.91 | TDP2 (0.44) | TDP2MRGPRX4PTGS2TP53TSHR | |
| SCHEMBL29095735 | 0.90 | MAPT (0.44) | TDP2MRGPRX4PTGS2TP53TSHR | |
| SCHEMBL29630219 | 0.90 | MAPT (0.44) | TDP2MRGPRX4PTGS2TP53TSHR | |
| SCHEMBL24484503 | 0.89 | SLC26A4 (0.42) | TDP2MRGPRX4LMNAKDM4EHTT | |
| SCHEMBL29630284 | 0.89 | SLC26A4 (0.42) | TDP2MRGPRX4LMNAKDM4EHTT | |
| SCHEMBL24485224 | 0.87 | TDP2 (0.42) | TDP2MRGPRX4PTGS2TP53TSHR | |
| SCHEMBL24484498 | 0.83 | PTGS2 (0.47) | PTGS2TSHRLMNAMAPTMAPK1 | |
| SCHEMBL29630207 | 0.83 | PTGS2 (0.47) | PTGS2TSHRLMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |