Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24485010 | 0.83 | SLC26A4 (0.67) | SLC26A4KMT2AMEN1PTGER4CASP3 | |
| SCHEMBL29630351 | 0.83 | SLC26A4 (0.67) | SLC26A4KMT2AMEN1PTGER4CASP3 | |
| SCHEMBL29095817 | 0.82 | PTGS2 (0.60) | SLC26A4KMT2AMEN1LMNAMAPT | |
| SCHEMBL24485013 | 0.75 | SLC26A4 (0.47) | SLC26A4KMT2AMEN1CASP3SENP8 | |
| SCHEMBL31723499 | 0.70 | CASP3 (0.45) | SLC26A4KMT2AMEN1CASP3SENP8 | |
| SCHEMBL17029329 | 0.68 | OPRL1 (0.41) | NMT1 | |
| SCHEMBL24485002 | 0.67 | SLC26A4 (0.65) | SLC26A4KMT2AMEN1PTGER4CASP3 | |
| SCHEMBL29629888 | 0.67 | SLC26A4 (0.65) | SLC26A4KMT2AMEN1PTGER4CASP3 | |
| SCHEMBL29095770 | 0.67 | PTGS2 (0.64) | SLC26A4KMT2AMEN1LMNAMAPT | |
| SCHEMBL24484904 | 0.67 | SLC26A4 (0.76) | SLC26A4KMT2AMEN1PTGER4CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |