Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL2958565 | 0.95 | GPR84 (0.50) | GAAGPR84FFAR1FFAR4CAMK2A | |
| SCHEMBL2964622 | 0.87 | MEN1 (0.41) | GAACYP4F2CYP4A11ALDH1A1EPHX2 | |
| SCHEMBL2949576 | 0.87 | MEN1 (0.41) | GAACYP4F2CYP4A11ALDH1A1EPHX2 | |
| Cadaverine Tartrate SCHEMBL2955530 | 0.84 | GAA (0.38) | GAACYP4F2CYP4A11ALDH1A1EPHX2 | |
| SCHEMBL2953064 | 0.83 | ALDH1A1 (0.38) | ALDH1A1EPHX2TSHRPLA2G2CDEGS1 | |
| Succinic Acid SCHEMBL22186968 | 0.82 | GPR84 (0.61) | GAAGPR84FFAR1FFAR4CAMK2A | |
| Malic Acid SCHEMBL2954331 | 0.82 | SMN1; SMN2 (0.46) | GAACYP4F2CYP4A11ALDH1A1EPHX2 | |
| Succinic Acid SCHEMBL2961696 | 0.82 | GAA (0.42) | GAAGPR84FFAR1FFAR4CAMK2A | |
| Succinic Acid SCHEMBL2962403 | 0.81 | MEN1 (0.42) | GPR84CAMK2AALDH1A1EPHX2TSHR | |
| Triethylene Glycol SCHEMBL2961975 | 0.81 | MEN1 (0.42) | GPR84CAMK2AALDH1A1EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7766978-B2 | Acidic hair dyeing method | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | H1-0, MRM1, H1-4 | GAA 4480/4885GPR84 845/4885FFAR1 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.