SCHEMBL29630686

SCHEMBL29630686

C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)NCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 13/20 0.38
OPRM1 P35372 9/20 0.38
OPRK1 P41145 2/20 0.38
SLC15A2 Q16348 1/20 0.37
GRPR P30550 3/20 0.35
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259179 0.91 SLC15A2 (0.38) SLC15A2
SCHEMBL259178 0.91 SLC15A2 (0.38) SLC15A2
SCHEMBL29591786 0.91 SLC15A2 (0.41) OPRD1OPRM1OPRK1SLC15A2GRPR
SCHEMBL29591894 0.89 SLC15A2 (0.41) OPRD1OPRM1OPRK1SLC15A2GRPR
SCHEMBL29630538 0.87 OPRD1 (0.38) OPRD1OPRM1OPRK1SLC15A2
SCHEMBL30455342 0.86 GRPR (0.37) OPRD1OPRM1OPRK1SLC15A2GRPR
SCHEMBL31323969 0.86 SLC15A2 (0.34) OPRD1OPRM1OPRK1SLC15A2GRPR
SCHEMBL30666376 0.85 OPRM1 (0.39) OPRD1OPRM1OPRK1SLC15A2GRPR
SCHEMBL30441904 0.85 SLC15A2 (0.37) OPRD1OPRM1OPRK1SLC15A2GRPR
SCHEMBL29590377 0.85 SLC15A2 (0.40) SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed