Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750456 | 1.00 | TRPV4 (0.47) | TRPV4MRGPRX4CHRNB2CHRNA4LIPE | |
| SCHEMBL29267532 | 0.92 | TRPV4 (0.41) | TRPV4MRGPRX4CHRNB2CHRNA4LIPE | |
| SCHEMBL28451946 | 0.76 | — | — | |
| SCHEMBL28702984 | 0.76 | L3MBTL1 (0.53) | LIPESCN9A | |
| SCHEMBL1890852 | 0.75 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL929327 | 0.75 | TRPV4 (0.52) | TRPV4MRGPRX4CHRNB2CHRNA4SCN9A | |
| SCHEMBL1146113 | 0.75 | TRPV4 (0.52) | TRPV4MRGPRX4CHRNB2CHRNA4SCN9A | |
| SCHEMBL14551864 | 0.74 | TRPV4 (0.47) | TRPV4MRGPRX4CHRNB2CHRNA4LIPE | |
| SCHEMBL581887 | 0.73 | TRPV4 (0.50) | TRPV4MRGPRX4CHRNB2CHRNA4LIPE | |
| SCHEMBL31130640 | 0.73 | TRPV4 (0.50) | TRPV4MRGPRX4CHRNB2CHRNA4LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111770918-B | Inhibitors of TRPC6 | 勃林格殷格翰国际公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| CN-110267959-B | Imidazo [1,5-A ] pyrazine derivatives as PI3K delta inhibitors | 百济神州有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |