Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20894244 | 1.00 | LMNA (0.56) | LMNACYP11B1CYP11B2CYP1A2CYP17A1 | |
| SCHEMBL3590613 | 0.87 | LMNA (0.56) | LMNACYP11B1CYP11B2CYP1A2CYP17A1 | |
| SCHEMBL10565741 | 0.87 | MAPT (0.58) | LMNACYP11B1CYP11B2CYP1A2CYP17A1 | |
| SCHEMBL1965892 | 0.85 | SMYD3 (0.60) | LMNAGAASMYD3ALDH1A1MAPT | |
| SCHEMBL31348187 | 0.85 | SMYD3 (0.60) | LMNAGAASMYD3ALDH1A1MAPT | |
| SCHEMBL10563001 | 0.84 | TMEM97 (0.46) | LMNACYP11B1CYP11B2CYP1A2CYP17A1 | |
| SCHEMBL10861761 | 0.83 | MAPT (0.46) | CYP11B1CYP11B2CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL10569727 | 0.83 | TMEM97 (0.45) | LMNACYP11B1CYP11B2CYP1A2CYP17A1 | |
| SCHEMBL7317599 | 0.82 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL8524330 | 0.82 | MAPT (0.52) | LMNACYP11B1CYP11B2CYP1A2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |