Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 18/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044800 | 0.82 | HRH3 (0.47) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL29631451 | 0.81 | JAK2 (0.41) | RET | |
| SCHEMBL29759418 | 0.79 | MAP2K1 (0.51) | RET | |
| SCHEMBL30725883 | 0.73 | RET (0.36) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL30175296 | 0.72 | RET (0.45) | RET | |
| SCHEMBL30175349 | 0.72 | CYP11B1 (0.41) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL30175294 | 0.72 | RET (0.43) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL30175367 | 0.71 | RET (0.48) | RET | |
| SCHEMBL30175281 | 0.70 | RET (0.41) | RET | |
| SCHEMBL25252185 | 0.69 | CDK2 (0.36) | RETDRD2DRD1DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115457-A9 | PYRAZOLO[1,5-A]PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2022-05-19 | — | — | WO | disclosed |