Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1519319 | 1.00 | TP53 (0.51) | TP53LMNAMTNR1AALOX15ALOX12 | |
| SCHEMBL24440178 | 1.00 | TP53 (0.51) | TP53LMNAMTNR1AALOX15ALOX12 | |
| SCHEMBL30292011 | 0.89 | TP53 (0.63) | TP53LMNAMTNR1APOLBMAPT | |
| SCHEMBL22165412 | 0.89 | TP53 (0.63) | TP53LMNAMTNR1APOLBMAPT | |
| SCHEMBL28379701 | 0.89 | TP53 (0.63) | TP53LMNAMTNR1APOLBMAPT | |
| SCHEMBL1519082 | 0.89 | TP53 (0.63) | TP53LMNAMTNR1APOLBMAPT | |
| SCHEMBL14013678 | 0.80 | MAPT (0.50) | TP53LMNAPOLBKDM4EMAPT | |
| SCHEMBL9441724 | 0.79 | ALOX15 (0.49) | TP53LMNAMTNR1AALOX15ALOX12 | |
| SCHEMBL10225789 | 0.79 | MTNR1A (0.51) | MTNR1ACYP19A1 | |
| SCHEMBL22617202 | 0.78 | MAOB (0.49) | TP53LMNAPOLBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103752-A1 | RAPID CONSTRUCTION OF TETRALIN, CHROMANE, AND INDANE MOTIFS VIA CYCLATIVE C-H/C-H COUPLING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-05-19 | — | — | WO | disclosed |