SCHEMBL29633587

SCHEMBL29633587

O=C(O)CC1Cc2ccccc2C1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.47
PREP P48147 6/20 0.44
TP53 P04637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP19A1 P11511 1/20 0.41
IDO1 P14902 1/20 0.41
MAPT P10636 3/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PRMT5 O14744 1/20 0.40
WDR77 Q9BQA1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1340255 1.00 DGAT1 (0.47) DGAT1PREPTP53L3MBTL1CYP19A1
SCHEMBL7304447 0.87 DGAT1 (0.58) DGAT1PREPCYP19A1MAPTALDH1A1
SCHEMBL7292707 0.87 DGAT1 (0.58) DGAT1PREPCYP19A1MAPTALDH1A1
SCHEMBL3406500 0.87 DGAT1 (0.58) DGAT1PREPCYP19A1MAPTALDH1A1
SCHEMBL30612421 0.87 DGAT1 (0.58) DGAT1PREPCYP19A1MAPTALDH1A1
Hydrochloric Acid SCHEMBL7389195 0.85 DGAT1 (0.56) DGAT1PREPCYP19A1MAPTALDH1A1
Hydrochloric Acid SCHEMBL7393121 0.85 DGAT1 (0.56) DGAT1PREPCYP19A1MAPTALDH1A1
SCHEMBL11461276 0.84 SIGMAR1 (0.52) TP53L3MBTL1CYP19A1
SCHEMBL8732825 0.83 AKR1B1 (0.39) DGAT1PREPTP53L3MBTL1GAA
SCHEMBL7072581 0.82 SLC6A1 (0.43) DGAT1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110183330-B Preparation method of 5, 6-diethyl-2, 3-dihydro-1H-indene-2-amine hydrochloride 安徽华邦药业有限公司 2022-05-27 CN claimed
CN-119823001-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-15 CN disclosed
CN-114206832-B Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-04 CN disclosed
CN-116490499-A Modulators of MYC family protooncogene proteins 纳罗医疗公司 2023-07-25 CN disclosed
CN-110914238-B Compounds as antibiotics 安塔比奥公司 2023-06-20 CN disclosed
EP-4048397-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME The Regents Of The University Of Michigan (US) 2022-08-31 EP disclosed
CN-110183330-B Preparation method of 5, 6-diethyl-2, 3-dihydro-1H-indene-2-amine hydrochloride 安徽华邦药业有限公司 2022-05-27 CN disclosed
CN-114206832-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2022-03-18 CN disclosed