Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23372828 | 1.00 | POLB (0.58) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL23357394 | 0.92 | POLB (0.49) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL23357398 | 0.90 | PTPN2 (0.49) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL23357439 | 0.89 | PTPN2 (0.48) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL23357559 | 0.89 | ALDH1A1 (0.50) | POLBPTPN2PTPN1ALDH1A1LMNA | |
| SCHEMBL23373031 | 0.88 | MEN1 (0.47) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL26999466 | 0.87 | POLB (0.49) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL26999472 | 0.87 | POLB (0.49) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL26999469 | 0.87 | POLB (0.49) | POLBPTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL26999470 | 0.87 | POLB (0.49) | POLBPTPN2PTPN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873315-B2 | Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2024-01-16 | — | — | US | disclosed |
| US-20220144868-A1 | CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS | The Board of Regents of the Nevada System of Higher Education on Behalf of the Univ of Nevada (US) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873315-B2 | Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts | ELANE, PNKP, SERPINB1 | POLB 1316/4885PTPN2 2417/4885PTPN1 1847/4885 |
| US-20220144868-A1 | CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS | ELANE, PNKP, NHERF1 | POLB 1299/4885PTPN2 2105/4885PTPN1 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.