Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633891 | 0.92 | ADRB3 (0.42) | ADRB3ADRB1FABP5KMT2ACASP3 | |
| SCHEMBL22091955 | 0.90 | FABP5 (0.39) | FABP5MEN1KMT2ATHRB | |
| SCHEMBL22091956 | 0.90 | FABP5 (0.39) | FABP5MEN1KMT2ATHRB | |
| SCHEMBL31369666 | 0.85 | FABP5 (0.44) | ADRB3ADRB1FABP5KMT2ATHRB | |
| SCHEMBL29633873 | 0.85 | FABP5 (0.44) | ADRB3ADRB1FABP5KMT2ATHRB | |
| SCHEMBL29633858 | 0.84 | PPARA (0.40) | FABP5KMT2ATHRB | |
| SCHEMBL22444730 | 0.84 | CASP3 (0.47) | ADRB3ADRB1CASP3 | |
| SCHEMBL29633794 | 0.82 | CHRM5 (0.42) | ADRB3ADRB1FABP5KMT2A | |
| SCHEMBL29633725 | 0.81 | FABP5 (0.41) | FABP5MEN1KMT2A | |
| SCHEMBL29633945 | 0.81 | FABP5 (0.35) | ADRB3ADRB1FABP5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376044-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2024-11-14 | — | — | US | disclosed |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-08-27 | — | — | US | disclosed |
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376044-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | ADRB3 1853/4885ADRB1 2567/4885FABP5 608/4885 |
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | ADRB3 1853/4885ADRB1 2567/4885FABP5 608/4885 |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | DDC, AADAT, TYR | ADRB3 1853/4885ADRB1 2567/4885FABP5 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.