Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.55 |
| ▸ | PPARG | P37231 | 8/20 | 0.55 |
| ▸ | PPARD | Q03181 | 8/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22108587 | 1.00 | PPARA (0.55) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL29633970 | 0.90 | LDHA (0.50) | PPARAPPARGPPARDLDHA | |
| SCHEMBL22108590 | 0.90 | LDHA (0.50) | PPARAPPARGPPARDLDHA | |
| SCHEMBL29633753 | 0.87 | PPARA (0.47) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL10065588 | 0.85 | LDHA (0.69) | PPARGLDHA | |
| SCHEMBL22445012 | 0.85 | LDHA (0.69) | PPARGLDHA | |
| SCHEMBL805254 | 0.85 | LDHA (0.69) | PPARGLDHA | |
| SCHEMBL31267220 | 0.85 | LDHA (0.69) | PPARGLDHA | |
| SCHEMBL22108690 | 0.84 | SLC7A5 (0.56) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL22444892 | 0.84 | SLC7A5 (0.56) | PPARAPPARGPPARDPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376044-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2024-11-14 | — | — | US | disclosed |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-08-27 | — | — | US | disclosed |
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376044-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | PPARA 658/4885PPARG 1123/4885PPARD 791/4885 |
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | PPARA 658/4885PPARG 1123/4885PPARD 791/4885 |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | DDC, AADAT, TYR | PPARA 658/4885PPARG 1123/4885PPARD 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.