Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22444620 | 1.00 | CASP3 (0.36) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL22454850 | 1.00 | CASP3 (0.36) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL24633697 | 0.91 | CASP3 (0.35) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL22444662 | 0.91 | NPSR1 (0.34) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL22444661 | 0.91 | NPSR1 (0.34) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL29633785 | 0.91 | NPSR1 (0.34) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL22454832 | 0.91 | NPSR1 (0.34) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL31135303 | 0.89 | CASP3 (0.39) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL30606806 | 0.89 | CASP3 (0.39) | CASP3NPSR1KMT2AFABP5FABP7 | |
| SCHEMBL22454759 | 0.89 | CASP3 (0.35) | CASP3NPSR1KMT2AFABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | CASP3 4077/4885NPSR1 2250/4885KMT2A 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.