SCHEMBL29633952

SCHEMBL29633952

CN(C(=O)OCC1c2ccccc2-c2ccccc21)C(CCc1ccc(F)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
FABP5 Q01469 2/20 0.35
MEN1 O00255 2/20 0.35
EPHX2 P34913 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
FABP7 O15540 1/20 0.33
ATM Q13315 1/20 0.33
MDM2 Q00987 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
CCR6 P51684 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4C Q9H3R0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633761 0.92 FABP5 (0.38) KMT2AFABP5EPHX2FABP7MDM2
SCHEMBL29633695 0.91 EPHX2 (0.35) KMT2AFABP5EPHX2FABP7MDM2
SCHEMBL29634036 0.91 MDM2 (0.38) KMT2AFABP5MEN1EPHX2FABP7
SCHEMBL29633663 0.90 PPIA (0.35) KMT2AFABP5EPHX2LMNAMAPT
SCHEMBL29633779 0.90 ADORA1 (0.36) KMT2AFABP5EPHX2FABP7MDM2
SCHEMBL29633980 0.90 FABP5 (0.36) KMT2AFABP5MEN1ALDH1A1LMNA
SCHEMBL29633993 0.90 EPHX2 (0.37) KMT2AMEN1EPHX2MAPTMDM2
SCHEMBL29633782 0.90 EPHX2 (0.34) KMT2AFABP5EPHX2ALDH1A1FABP7
SCHEMBL29633784 0.90 MDM2 (0.37) FABP5EPHX2ALDH1A1MDM2FFAR1
SCHEMBL25354435 0.88 FABP5 (0.39) KMT2AFABP5MEN1EPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR KMT2A 355/4885FABP5 608/4885MEN1 3483/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR KMT2A 355/4885FABP5 608/4885MEN1 3483/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR KMT2A 355/4885FABP5 608/4885MEN1 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.