SCHEMBL29633779

SCHEMBL29633779

CN(C(=O)OCC1c2ccccc2-c2ccccc21)C(CCc1ccc(Cl)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.36
FABP5 Q01469 3/20 0.36
FABP7 O15540 2/20 0.36
EPHX2 P34913 1/20 0.34
KMT2A Q03164 1/20 0.34
MDM2 Q00987 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633761 0.92 FABP5 (0.38) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL29633782 0.91 EPHX2 (0.34) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL29633695 0.91 EPHX2 (0.35) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL29633952 0.90 KMT2A (0.35) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL29633971 0.90 ADORA1 (0.39) ADORA1FABP5FABP7KMT2ACYP3A4
SCHEMBL29633793 0.90 EPHX2 (0.37) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL29633784 0.90 MDM2 (0.37) FABP5EPHX2MDM2FFAR1FFAR4
SCHEMBL29634036 0.89 MDM2 (0.38) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL29633751 0.89 FABP5 (0.40) FABP5FABP7EPHX2KMT2AMDM2
SCHEMBL21837719 0.88 FABP5 (0.40) FABP5FABP7EPHX2KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR ADORA1 2955/4885FABP5 608/4885FABP7 1148/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR ADORA1 2955/4885FABP5 608/4885FABP7 1148/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR ADORA1 2955/4885FABP5 608/4885FABP7 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.