Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.65 |
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 13/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 7/20 | 0.53 |
| ▸ | BCL2 | P10415 | 5/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.52 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.52 |
| ▸ | BCL2L2 | Q92843 | 4/20 | 0.52 |
| ▸ | HK1 | P19367 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | CFTR | P13569 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GOPC | Q9HD26 | 3/20 | 0.51 |
| ▸ | TDP2 | O95551 | 3/20 | 0.51 |
| ▸ | NSD2 | O96028 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28711122 | 1.00 | EP300 (0.65) | EP300STAT3MCL1HKDC1BCL2 | |
| SCHEMBL1428457 | 0.79 | EP300 (1.00) | EP300STAT3MCL1HKDC1BCL2 | |
| SCHEMBL2241702 | 0.79 | BCL2A1 (0.66) | MCL1HKDC1BCL2BCL2L1BCL2A1 | |
| SCHEMBL13509804 | 0.73 | STAT3 (0.73) | EP300STAT3MCL1MEN1KMT2A | |
| SCHEMBL588908 | 0.71 | HKDC1 (0.60) | EP300MCL1HKDC1BCL2BCL2L1 | |
| SCHEMBL13780715 | 0.71 | EP300 (0.70) | EP300STAT3MCL1HKDC1BCL2 | |
| SCHEMBL10823344 | 0.71 | EP300 (0.50) | EP300STAT3MCL1HKDC1BCL2 | |
| SCHEMBL7196466 | 0.70 | KMT2A (0.75) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2241344 | 0.69 | MCL1 (1.00) | EP300STAT3MCL1HKDC1BCL2 | |
| SCHEMBL13510461 | 0.69 | EP300 (0.71) | EP300STAT3MCL1HKDC1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206329-A | Combination therapy methods, compositions and kits | 阿库尔疗法公司 | 2022-03-18 | — | — | CN | claimed |
| CN-114206329-A | Combination therapy methods, compositions and kits | 阿库尔疗法公司 | 2022-03-18 | — | — | CN | disclosed |