Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.47 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.46 |
| ▸ | HK1 | P19367 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823663 | 0.90 | LMNA (0.47) | EP300BRAFLMNAMEN1KMT2A | |
| SCHEMBL10823564 | 0.88 | MAPT (0.53) | MCL1HKDC1LMNABCL2BCL2L1 | |
| SCHEMBL10823732 | 0.87 | KMT2A (0.50) | EP300HKDC1LMNAMEN1KMT2A | |
| SCHEMBL10823573 | 0.84 | MCL1 (0.45) | EP300MCL1HKDC1LMNABCL2 | |
| SCHEMBL10823495 | 0.84 | IDH1 (0.56) | MEN1KMT2AG6PD | |
| SCHEMBL10823667 | 0.83 | MEN1 (0.44) | EP300BRAFHKDC1LMNAMEN1 | |
| SCHEMBL10823391 | 0.83 | HKDC1 (0.48) | EP300HKDC1LMNAMEN1KMT2A | |
| SCHEMBL10823431 | 0.82 | CHEK1 (0.45) | EP300HKDC1LMNAMEN1KMT2A | |
| SCHEMBL10823709 | 0.82 | LMNA (0.52) | EP300HKDC1LMNAMEN1KMT2A | |
| SCHEMBL11344786 | 0.81 | TIMP3 (0.54) | EP300MCL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |