SCHEMBL2963410

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2668888	0.92	LMNA (0.32)	MEN1KMT2ANPSR1LMNAHPGD
	SCHEMBL2977649	0.90	MAPT (0.34)	MEN1KMT2ANPSR1LMNAHPGD
	SCHEMBL2968130	0.89	ALDH1A1 (0.34)	NPSR1LMNAHPGDRAB9AALDH1A1
	SCHEMBL2659944	0.89	LMNA (0.33)	NPSR1LMNAHPGDRAB9AALDH1A1
	SCHEMBL2668876	0.89	MEN1 (0.31)	MEN1KMT2ANPSR1LMNAHPGD
	SCHEMBL13204116	0.89	ALDH1A1 (0.38)	MEN1KMT2ANPSR1LMNAHPGD
	SCHEMBL2976579	0.89	LMNA (0.32)	NPSR1LMNAHPGDRAB9AALDH1A1
	SCHEMBL2963215	0.88	LMNA (0.32)	MEN1KMT2ANPSR1LMNAHPGD
	SCHEMBL2963079	0.88	LMNA (0.32)	LMNAHPGDALDH1A1MAPT
	SCHEMBL2963424	0.87	MAPT (0.34)	MEN1KMT2ANPSR1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.