Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160528 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL29663893 | 0.94 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL164352 | 0.94 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL722895 | 0.93 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL23803978 | 0.77 | AHR (0.41) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL6206954 | 0.76 | TNKS (0.37) | ALDH1A1HSD17B10HIF1AHPGDCYP1B1 | |
| SCHEMBL1309270 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL30476322 | 0.76 | CYP1A2 (0.46) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL6201679 | 0.75 | CYP1A2 (0.46) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL14358959 | 0.71 | MAOA (0.46) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11874434-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20220137262-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS | JOHNSON & JOHNSON VISION CARE (US) | 2022-05-05 | — | — | US | disclosed |