Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634291 | 0.76 | ALDH1A1 (0.39) | KMT2AMAPTRAB9AMEN1ESR1 | |
| SCHEMBL722895 | 0.76 | ALDH1A1 (0.39) | KMT2AMAPTRAB9AMEN1ESR1 | |
| SCHEMBL160528 | 0.76 | ALDH1A1 (0.39) | KMT2AMAPTRAB9AMEN1ESR1 | |
| SCHEMBL29663893 | 0.74 | ALDH1A1 (0.40) | NQO2KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL164352 | 0.74 | ALDH1A1 (0.40) | NQO2KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL19876303 | 0.71 | — | — | |
| SCHEMBL4159164 | 0.71 | TRPM4 (0.47) | TNKSTNKS2NQO1NQO2KMT2A | |
| SCHEMBL14951318 | 0.71 | PTPN1 (0.46) | TNKSTNKS2NQO1NQO2KMT2A | |
| SCHEMBL16283926 | 0.71 | ALDH1A1 (0.46) | TNKSTNKS2NQO1NQO2KMT2A | |
| SCHEMBL17383050 | 0.71 | NQO2 (0.44) | TNKSTNKS2NQO1NQO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881850-B2 | Heterocyclically annellated indenochromene derivatives | RODENSTOCK GMBH (DE) | 2005-04-19 | — | — | US | disclosed |
| EP-1144416-B1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | RODENSTOCK GMBH (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | OPTISCHE WERKE G. RODENSTOCK | 2004-05-13 | — | — | US | disclosed |
| US-6660727-B1 | Photochromic heterocyclically anellated indenochromene compounds | RODENSTOCK GMBH (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1144416-A1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | Optische Werke G. Rodenstock (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2001034609-A1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | ALDH1A2, INF2, CYP1B1 | TNKS 2455/4885TNKS2 1391/4885NQO1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.