SCHEMBL2963466

SCHEMBL2963466

CC1C(c2cccc3ccccc23)=Cc2c(Br)cccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.33
ALDH1A1 P00352 5/20 0.33
MAPT P10636 4/20 0.33
HPGD P15428 3/20 0.33
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CYP11B2 P19099 1/20 0.33
TDP2 O95551 1/20 0.33
ALOX12 P18054 1/20 0.33
CASP3 P42574 1/20 0.33
HTT P42858 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
PTPN1 P18031 1/20 0.33
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2967826 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2966542 0.77 CYP11B2 (0.33) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL2973975 0.76 ALDH1A1 (0.35) ALDH1A1MAPK1KDM1ARAB9ANPC1
SCHEMBL2963322 0.75 MAPK1 (0.35) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL2960245 0.74 CYP1A2 (0.34) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL1451820 0.71 CA12 (0.33) ALDH1A1MAPTHPGDMEN1GAA
SCHEMBL1452836 0.71 CA12 (0.33) ALDH1A1MAPTHPGDMEN1GAA
SCHEMBL2968937 0.71 NPC1 (0.34) MAPK1L3MBTL1SMN1; SMN2TP53NFKB1
SCHEMBL17952999 0.71 ALDH1A1 (0.37) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL1452672 0.70 ENPP3 (0.33) KDM4EALDH1A1MAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 KDM4E 2177/4885ALDH1A1 4332/4885MAPT 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.