SCHEMBL29634740

SCHEMBL29634740

COc1ccc(N)c(NCCO)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.43
KDM4E B2RXH2 4/20 0.42
MAPK1 P28482 2/20 0.42
HTT P42858 3/20 0.40
RAD52 P43351 3/20 0.40
USP2 O75604 1/20 0.40
TSHR P16473 1/20 0.40
TAAR1 Q96RJ0 1/20 0.38
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 2/20 0.36
KMT2A Q03164 1/20 0.36
NR1I2 O75469 1/20 0.36
AHR P35869 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
PDE5A O76074 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94186 1.00 TNF (0.43) TNFKDM4EMAPK1HTTRAD52
Hydrochloric Acid SCHEMBL7591939 0.98 TNF (0.43) TNFKDM4EMAPK1HTTRAD52
SCHEMBL6925243 0.90 TNF (0.40) TNFKDM4EMAPK1HTTRAD52
SCHEMBL6669525 0.88 TNF (0.36) TNFKDM4EMAPK1HTTRAD52
SCHEMBL12046243 0.85 APP (0.45) KDM4EALDH1A1HSD17B10PDE5AHPGD
SCHEMBL198171 0.84 LDHA (0.43) KDM4EMAPK1HTTUSP2TSHR
SCHEMBL5833312 0.84 MTNR1A (0.37) TNFUSP2ALDH1A1HSD17B10MTNR1A
SCHEMBL29393618 0.84 LDHA (0.43) KDM4EMAPK1HTTUSP2TSHR
SCHEMBL2270023 0.82 RAD52 (0.46) MAPK1RAD52ALDH1A1POLBKMT2A
SCHEMBL2272035 0.81 HRH3 (0.43) RAD52POLBPDE5APDE6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4051219-A1 AQUEOUS OXIDIZING COMPOSITION COMPRISING AMINO ACIDS Kao Corporation (JP) 2022-09-07 EP disclosed