Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.34 |
| ▸ | PDE6A | P16499 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94186 | 0.90 | TNF (0.43) | TNFHTTKDM4EMAPK1TAAR1 | |
| SCHEMBL29634740 | 0.90 | TNF (0.43) | TNFHTTKDM4EMAPK1TAAR1 | |
| Hydrochloric Acid SCHEMBL7591939 | 0.89 | TNF (0.43) | TNFHTTKDM4EMAPK1TAAR1 | |
| SCHEMBL6669525 | 0.80 | TNF (0.36) | TNFHTTKDM4EMAPK1TAAR1 | |
| SCHEMBL6925238 | 0.77 | POLB (0.34) | HTTTSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL12046243 | 0.77 | APP (0.45) | KDM4EALDH1A1HSD17B10PDE5AHPGD | |
| SCHEMBL5833312 | 0.76 | MTNR1A (0.37) | TNFUSP2ALDH1A1HSD17B10TLR8 | |
| SCHEMBL198171 | 0.76 | LDHA (0.43) | HTTKDM4EMAPK1USP2TSHR | |
| SCHEMBL29393618 | 0.76 | LDHA (0.43) | HTTKDM4EMAPK1USP2TSHR | |
| SCHEMBL2270023 | 0.74 | RAD52 (0.46) | MAPK1RAD52ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003075871-A1 | METHOD OF GRADUAL PERMANENT COLORING OF HAIR | UNILEVER PLC (GB) | 2003-09-18 | — | — | WO | claimed |
| WO-2003075870-A1 | GRADUAL PERMANENT COLOURING OF HAIR USING DYE INTERMEDIATES DISSOLVED IN ALKALINE AQUEOUS MEDIUM COMPRISING A GELLING AGENT | UNILEVER PLC (GB) | 2003-09-18 | — | — | WO | claimed |
| WO-2003075870-A1 | GRADUAL PERMANENT COLOURING OF HAIR USING DYE INTERMEDIATES DISSOLVED IN ALKALINE AQUEOUS MEDIUM COMPRISING A GELLING AGENT | UNILEVER PLC (GB) | 2003-09-18 | — | — | WO | disclosed |
| WO-2003055458-A1 | GRADUAL PERMANENT COLORING OF HAIR USING DYE INTERMEDIATES IN A SHAMPOO BASE | UNILEVER PLC (GB) | 2003-07-10 | — | — | WO | disclosed |