Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988105 | 1.00 | CA2 (0.45) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL4984284 | 0.89 | CA2 (0.42) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL4987706 | 0.88 | CHRM1 (0.44) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL8421695 | 0.85 | CA2 (0.50) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL28570001 | 0.83 | CA2 (0.48) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL4470713 | 0.83 | CA2 (0.54) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL6431145 | 0.83 | CA2 (0.54) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL27610235 | 0.82 | ALDH1A1 (0.54) | CA2MAPK1SLC1A2SLC1A1ACE2 | |
| SCHEMBL986357 | 0.80 | GPR84 (0.53) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL9955627 | 0.80 | GPR84 (0.53) | CA2MAPK1ACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585637-B | MASP-inhibitory compounds and uses thereof | 拜耳公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114585637-A | MASP inhibiting compounds and uses thereof | 拜耳公司 | 2022-06-03 | — | — | CN | disclosed |