SCHEMBL29634965

SCHEMBL29634965

COC(=O)COc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2OC)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK2 O00142 10/20 0.52
PYGM P11217 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546996 0.91 PYGM (0.57) TK2PYGM
SCHEMBL14853756 0.91 PYGM (0.57) TK2PYGM
SCHEMBL14930959 0.91 PYGM (0.57) TK2PYGM
SCHEMBL14929088 0.91 PYGM (0.57) TK2PYGM
SCHEMBL14842287 0.91 PYGM (0.57) TK2PYGM
SCHEMBL26370054 0.88 PYGM (0.47) TK2PYGM
SCHEMBL442314 0.87 PYGM (0.53) TK2PYGM
SCHEMBL31155735 0.86 P2RY6 (0.53) TK2PYGM
SCHEMBL19614649 0.84 TK2 (0.53) TK2PYGM
SCHEMBL2027440 0.84 TK2 (0.53) TK2PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025052108-A2 RNA MOLECULE IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-03-13 WO disclosed
WO-2025038850-A1 LIPID NANOPARTICLES AND METHODS FOR SENSITIZING RESPONSE TO AN IMMUNOTHERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 WO disclosed
EP-4486909-A2 RNA MOLECULE Imperial College Innovations Limited (GB) 2025-01-08 EP disclosed
EP-4240396-A1 USE OF IFN-LAMBDA MRNA FOR TREATING VIRAL INFECTIONS Ethris GmbH (DE) 2023-09-13 EP disclosed
WO-2023166314-A2 RNA MOLECULE IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2023-09-07 WO disclosed
WO-2022096582-A1 USE OF IFN-LAMBDA MRNA FOR TREATING VIRAL INFECTIONS ETHRIS GMBH (DE) 2022-05-12 WO disclosed