Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.48 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 6/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600734 | 0.83 | CALCRL (0.51) | PSMB5CDYL2CDYLBACE1STAT3 | |
| SCHEMBL29674863 | 0.80 | BACE1 (0.49) | BACE1 | |
| SCHEMBL30558305 | 0.75 | NPY4R (0.51) | BACE1 | |
| SCHEMBL31720970 | 0.74 | BACE1 (0.65) | BACE1 | |
| SCHEMBL17732675 | 0.74 | BACE1 (0.56) | BACE1 | |
| SCHEMBL31474502 | 0.74 | OPRM1 (0.53) | BACE1 | |
| SCHEMBL30735528 | 0.74 | MME (0.57) | — | |
| SCHEMBL233444 | 0.74 | MME (0.60) | — | |
| SCHEMBL31174325 | 0.74 | MME (0.60) | — | |
| SCHEMBL233445 | 0.74 | MME (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997104-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | disclosed |