Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036872 | 0.94 | DPP4 (0.42) | ALDH1A1DPP4GRIK1GRIK2GRM2 | |
| SCHEMBL28285666 | 0.79 | DPP4 (0.36) | ALDH1A1DPP4GRIK1GRIK2 | |
| SCHEMBL16276999 | 0.78 | GRM8 (0.52) | DPP4GRIK1GRIK2TSHRGRM2 | |
| SCHEMBL30150927 | 0.78 | PTGS1 (0.43) | ALDH1A1GRIK1CES2CES1TSHR | |
| SCHEMBL3366847 | 0.78 | HSD11B1 (0.42) | ALDH1A1DPP4GRIK1CES2CES1 | |
| SCHEMBL30882711 | 0.76 | DPP7 (0.46) | ALDH1A1DPP4CES2CES1TSHR | |
| SCHEMBL27557531 | 0.76 | ALDH1A1 (0.43) | ALDH1A1DPP4GRIK1CES2CES1 | |
| Biphenyl SCHEMBL7779237 | 0.76 | GRIK1 (0.53) | ALDH1A1DPP4GRIK1GRIK2GRM2 | |
| SCHEMBL30526382 | 0.76 | GRIK1 (0.40) | ALDH1A1DPP4GRIK1CES2CES1 | |
| SCHEMBL31596848 | 0.74 | GRM8 (0.52) | DPP4GRIK1GRIK2TSHRGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997104-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | disclosed |