Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.43 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796393 | 1.00 | NPY5R (0.44) | NPY5RROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL29635205 | 0.78 | AURKA (0.47) | NPY5RCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL28359047 | 0.78 | AURKA (0.47) | NPY5RCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL29635176 | 0.74 | CYP11B2 (0.41) | NPY5RROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL28796486 | 0.74 | CYP11B2 (0.41) | NPY5RROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL28359195 | 0.72 | CYP11B1 (0.52) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL29635118 | 0.72 | CYP11B1 (0.52) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL28796377 | 0.71 | NPY5R (0.43) | NPY5RPIM1ALDH1A1MAPTKMT2A | |
| SCHEMBL29635192 | 0.71 | NPY5R (0.43) | NPY5RPIM1ALDH1A1MAPTKMT2A | |
| SCHEMBL13735404 | 0.70 | HDAC3 (0.55) | ROCK2ROCK1CDC42BPBCDC42BPACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248472-B | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2022-06-28 | — | — | CN | disclosed |