Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796377 | 1.00 | NPY5R (0.43) | NPY5RALDH1A1SMN1; SMN2PIM1ALDH1A3 | |
| SCHEMBL28796393 | 0.71 | NPY5R (0.44) | NPY5RALDH1A1PIM1MAPTKMT2A | |
| SCHEMBL29635147 | 0.71 | NPY5R (0.44) | NPY5RALDH1A1PIM1MAPTKMT2A | |
| SCHEMBL30297945 | 0.68 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2ALDH1A3L3MBTL1GAA | |
| SCHEMBL28796378 | 0.68 | CYP2A6 (0.37) | — | |
| SCHEMBL29267034 | 0.68 | IDO1 (0.36) | PIM1 | |
| SCHEMBL15854536 | 0.66 | TSHR (0.41) | ALDH1A1SMN1; SMN2ALDH1A3L3MBTL1GAA | |
| SCHEMBL3633987 | 0.66 | ERN1 (0.40) | ALDH1A1SMN1; SMN2PIM1L3MBTL1GAA | |
| SCHEMBL15854543 | 0.65 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ALDH1A3L3MBTL1GAA | |
| SCHEMBL3636860 | 0.65 | CYP19A1 (0.38) | GAAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248472-B | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2022-06-28 | — | — | CN | disclosed |