Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 5/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796486 | 1.00 | CYP11B2 (0.41) | CYP11B2CYP11B1ROCK1ROCK2CDC42BPB | |
| SCHEMBL28796397 | 0.81 | AURKA (0.43) | ROCK1WNT1DYRK1APIM1BRD4 | |
| SCHEMBL29635084 | 0.81 | AURKA (0.43) | ROCK1WNT1DYRK1APIM1BRD4 | |
| SCHEMBL28796391 | 0.79 | BRD4 (0.40) | ROCK1WNT1DYRK1APIM1BRD4 | |
| SCHEMBL29635045 | 0.79 | BRD4 (0.40) | ROCK1WNT1DYRK1APIM1BRD4 | |
| SCHEMBL29635053 | 0.76 | PRKCZ (0.40) | ROCK1WNT1DYRK1APIM1BRD4 | |
| SCHEMBL28362692 | 0.74 | KDM4E (0.43) | BRD4ALDH1A1ALOX12CYP3A4CYP2C9 | |
| SCHEMBL29635098 | 0.74 | KDM4E (0.43) | BRD4ALDH1A1ALOX12CYP3A4CYP2C9 | |
| SCHEMBL29635147 | 0.74 | NPY5R (0.44) | CYP11B2CYP11B1ROCK1ROCK2CDC42BPB | |
| SCHEMBL28796393 | 0.74 | NPY5R (0.44) | CYP11B2CYP11B1ROCK1ROCK2CDC42BPB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248472-B | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2022-06-28 | — | — | CN | claimed |
| CN-113248472-B | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2022-06-28 | — | — | CN | disclosed |