Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552608 | 0.93 | MDM2 (0.46) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL31606668 | 0.93 | MDM2 (0.46) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL22552606 | 0.93 | MDM2 (0.46) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL20825486 | 0.89 | MDM2 (0.42) | MDM2MDM4TP53NFKB1NFKB2 | |
| SCHEMBL20825490 | 0.89 | MDM2 (0.42) | MDM2MDM4TP53NFKB1NFKB2 | |
| SCHEMBL22580196 | 0.84 | SYK (0.48) | — | |
| SCHEMBL20825644 | 0.84 | SYK (0.48) | — | |
| SCHEMBL22580212 | 0.82 | KMT2A (0.45) | TLR2 | |
| SCHEMBL22579992 | 0.82 | MDM2 (0.48) | MDM2MDM4TP53TNFCASP3 | |
| SCHEMBL20825492 | 0.82 | KMT2A (0.45) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681875-B1 | CYCLIC PEPTIDE ANTIBIOTICS | HOFFMANN LA ROCHE (CH) | 2026-01-14 | — | — | EP | disclosed |
| US-11279735-B2 | Cyclic peptide antibiotics | GENENTECH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279735-B2 | Cyclic peptide antibiotics | NPPA, LNPEP, CLPP | MDM2 2362/4885MDM4 3536/4885TP53 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.