Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.58 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585062 | 0.98 | KDM4E (0.68) | KDM4EL3MBTL1MAPK1P4HTMP4HA1 | |
| SCHEMBL1971939 | 0.88 | MAPK1 (0.61) | KDM4EL3MBTL1MAPK1CYP2C9CYP2C19 | |
| SCHEMBL29637478 | 0.88 | MAPK1 (0.61) | KDM4EL3MBTL1MAPK1CYP2C9CYP2C19 | |
| SCHEMBL370722 | 0.85 | P4HTM (0.59) | KDM4EL3MBTL1MAPK1P4HTMP4HA1 | |
| SCHEMBL7356681 | 0.84 | MAPK1 (0.75) | KDM4EL3MBTL1MAPK1CA12CA1 | |
| SCHEMBL2963598 | 0.83 | MAPK1 (0.50) | KDM4EL3MBTL1MAPK1P4HTMCYP2C9 | |
| SCHEMBL2108606 | 0.83 | P4HTM (0.56) | KDM4EL3MBTL1MAPK1P4HTMP4HA1 | |
| SCHEMBL27429591 | 0.82 | L3MBTL1 (0.59) | KDM4EL3MBTL1MAPK1P4HTMP4HA1 | |
| SCHEMBL27305364 | 0.81 | MAPK1 (0.49) | KDM4EL3MBTL1MAPK1CYP2C9CYP2C19 | |
| SCHEMBL23149647 | 0.80 | KDM4E (0.56) | KDM4EL3MBTL1MAPK1P4HTMP4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | KDM4E 514/4885L3MBTL1 550/4885MAPK1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.