SCHEMBL370722

SCHEMBL370722

CCOC(=O)c1ccc(C(=O)O)cn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 4/20 0.59
P4HA1 P13674 2/20 0.59
MIF P14174 1/20 0.59
MAPT P10636 1/20 0.58
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
CYP1A2 P05177 2/20 0.50
HCAR3 P49019 6/20 0.49
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ESR1 P03372 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
ESR2 Q92731 1/20 0.47
CA14 Q9ULX7 1/20 0.47
GABRP O00591 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1971939 0.90 MAPK1 (0.61) MAPTMAPK1L3MBTL1KDM4ECYP2C9
SCHEMBL29637478 0.90 MAPK1 (0.61) MAPTMAPK1L3MBTL1KDM4ECYP2C9
SCHEMBL2349837 0.87 P4HA1 (0.56) P4HTMP4HA1MIFMAPTMAPK1
SCHEMBL16998556 0.87 MAPK1 (0.53) P4HTMMAPTMAPK1L3MBTL1KDM4E
SCHEMBL2585062 0.87 KDM4E (0.68) P4HTMP4HA1MIFMAPTMAPK1
SCHEMBL2963596 0.85 KDM4E (0.66) P4HTMP4HA1MIFMAPTMAPK1
SCHEMBL11386893 0.85 MAPK1 (0.51) MAPTMAPK1L3MBTL1KDM4ECYP1A2
SCHEMBL5127677 0.84 P4HA1 (0.53) P4HTMP4HA1MIFMAPTMAPK1
SCHEMBL2412458 0.84 MAPK1 (0.50) MAPTMAPK1L3MBTL1KDM4ECYP1A2
SCHEMBL2109944 0.84 MAPK1 (0.50) MAPTMAPK1L3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357210-A1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE NIHON NOHYAKU CO., LTD. (JP) 2023-11-09 US disclosed
WO-2022092180-A1 NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE THEREOF 日本農薬株式会社 2022-05-05 WO disclosed
CN-108137568-A Fused heterocyclic compound having oxime group or salt thereof, agricultural and horticultural insecticide containing fused heterocyclic compound, and method of using fused heterocyclic compound or salt thereof 日本农药株式会社 2018-06-08 CN disclosed
US-9682953-B2 Amide compounds, compositions and applications thereof ADVINUS THERAPEUTICS LIMITED (IN) 2017-06-20 US disclosed
US-9682953-B2 Amide compounds, compositions and applications thereof ADVINUS THERAPEUTICS LIMITED (IN) 2017-06-20 US disclosed
US-9682953-B2 Amide compounds, compositions and applications thereof ADVINUS THERAPEUTICS LIMITED (IN) 2017-06-20 US disclosed
WO-2016202875-A1 PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM BIOME BIOPLASTICS LIMITED (GB) 2016-12-22 WO disclosed
CN-103958473-B Amide compound, composition and application thereof ADVINUS THERAPEUTICS LTD. (IN) 2016-11-30 CN disclosed
US-20150065464-A1 AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF ADVINUS THERAPEUTICS LIMITED (IN) 2015-03-05 US disclosed
CN-103958473-A Amide compound, composition and application thereof ADVINUS THERAPEUTICS LTD 2014-07-30 CN disclosed
EP-0850909-A1 Stilbene compounds with adamantyl group, compositions containing the same and uses CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) 1998-07-01 EP disclosed
EP-0679631-B1 Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use CIRD GALDERMA (FR) 1998-05-06 EP disclosed
EP-0776885-A1 Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) 1997-06-04 EP disclosed
US-5574036-A Adamantyl-substituted polycyclic acetylene compounds and pharmaceutical/cosmetic compositions comprised thereof CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) 1996-11-12 US disclosed
EP-0679631-A1 Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) 1995-11-02 EP disclosed
CN-1109875-A Phenyl-substituted 1,4-dihydropyridines BAYER AG (DE) 1995-10-11 CN disclosed
EP-0267794-B1 PROCESS FOR PREPARING POLYOLEFINS Nippon Petrochemicals Co., Ltd. (JP) 1993-05-05 EP disclosed
EP-0267794-A2 Process for preparing polyolefins Nippon Petrochemicals Co., Ltd. (JP) 1988-05-18 EP disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed
US-4273779-A Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids CIBA-GEIGY CORPORATION (US) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357210-A1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE DDT, HDHD5, HPD P4HTM 1111/4885P4HA1 246/4885MIF 4120/4885
US-20150065464-A1 AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF FAAH, FAAH2, TPH1 P4HTM 1093/4885P4HA1 941/4885MIF 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.