Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR5A | P47898 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742322 | 0.86 | HTR1B (0.53) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL28229274 | 0.85 | HTR1B (0.65) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL18498486 | 0.84 | MEN1 (0.59) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| Tryptamine SCHEMBL29693568 | 0.82 | HTR7 (0.73) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| Tryptamine SCHEMBL29565321 | 0.82 | HTR7 (0.73) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL1519983 | 0.81 | HTR2A (0.54) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8700750 | 0.81 | SMN1; SMN2 (0.51) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL27893589 | 0.80 | GLS (0.43) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL13253481 | 0.77 | MEN1 (0.55) | HTR1BHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL17732259 | 0.77 | MEN1 (0.58) | HTR1BHTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195451-B2 | Compositions and methods for viral sensitization | Ottawa Hospital Research Institute and University of Ottawa (CA) | 2025-01-14 | — | — | US | disclosed |
| US-20240360115-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2024-10-31 | — | — | US | disclosed |
| EP-3250550-B1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RES INST (CA) | 2023-04-05 | — | — | EP | disclosed |
| US-20220220101-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2022-07-14 | — | — | US | disclosed |
| US-11339146-B2 | Compositions and methods for viral sensitization | Ottawa Hospital Research Institute and University of Ottawa (CA) | 2022-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195451-B2 | Compositions and methods for viral sensitization | CD4, CD74, HLA-DRB1 | HTR1B 4623/4885HTR2A 4754/4885HTR2C 4344/4885 |
| US-11339146-B2 | Compositions and methods for viral sensitization | CD4, CD74, HLA-DRB1 | HTR1B 4401/4885HTR2A 4431/4885HTR2C 4250/4885 |
| US-20220220101-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | CD4, CD74, HAVCR2 | HTR1B 4571/4885HTR2A 4597/4885HTR2C 4558/4885 |
| US-20240360115-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | CD4, CD74, HAVCR2 | HTR1B 4571/4885HTR2A 4597/4885HTR2C 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.