SCHEMBL29636243

SCHEMBL29636243

Nc1ccc2c(c1)C1c3ccccc3C2c2ccc(N)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
CASP1 P29466 2/20 0.48
RECQL P46063 1/20 0.48
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 2/20 0.44
CDK5 Q00535 2/20 0.42
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42
ABL1 P00519 1/20 0.42
NTRK1 P04629 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
IGF1R P08069 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL807465 1.00 CYP3A4 (0.48) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL23567922 1.00 CYP3A4 (0.48) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL29549133 1.00 CYP3A4 (0.48) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL10070929 0.92 CYP3A4 (0.47) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL18682060 0.92 CYP3A4 (0.47) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL17678877 0.91 ALDH1A1 (0.54) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL19307997 0.87 ACHE (0.42) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL29457161 0.83 CYP3A4 (0.37) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL24524178 0.81 ALDH1A1 (0.64) CYP3A4CASP1RECQLALDH1A1HSD17B10
SCHEMBL17789217 0.78 ACHE (0.46) CYP3A4CASP1RECQLALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117919946-B Sea water desalination reverse osmosis composite membrane and preparation method and application thereof 中山大学 2024-06-18 CN claimed
CN-117919946-A Sea water desalination reverse osmosis composite membrane and preparation method and application thereof 中山大学 2024-04-26 CN claimed
CN-117225188-A Preparation method of organic solvent nanofiltration membrane of rigid-flexible dual-network type IPN 浙江大学 2023-12-15 CN claimed
CN-115779684-A Nanofiltration membrane and preparation method and application thereof 北京碧水源膜科技有限公司 2023-03-14 CN claimed
CN-119192573-A Modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2024-12-27 CN disclosed
CN-119060338-A Modified maleimide prepolymer, resin composition and application thereof 常熟生益科技有限公司 2024-12-03 CN disclosed
WO-2024233919-A2 CONTORTED POLYAMIDE MEMBRANES AND METHODS OF USE THEREOF UNIVERSITY OF HOUSTON SYSTEM (US) 2024-11-14 WO disclosed
CN-117919946-B Sea water desalination reverse osmosis composite membrane and preparation method and application thereof 中山大学 2024-06-18 CN disclosed
CN-117919946-A Sea water desalination reverse osmosis composite membrane and preparation method and application thereof 中山大学 2024-04-26 CN disclosed
CN-117225188-A Preparation method of organic solvent nanofiltration membrane of rigid-flexible dual-network type IPN 浙江大学 2023-12-15 CN disclosed
CN-115779684-A Nanofiltration membrane and preparation method and application thereof 北京碧水源膜科技有限公司 2023-03-14 CN disclosed
CN-111111475-B Preparation method of graphene oxide modified triptycenyl polyamide separation membrane 南京工业大学 2022-03-22 CN disclosed