Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23567922 | 1.00 | CYP3A4 (0.48) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL29549133 | 1.00 | CYP3A4 (0.48) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL29636243 | 1.00 | CYP3A4 (0.48) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL10070929 | 0.92 | CYP3A4 (0.47) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL18682060 | 0.92 | CYP3A4 (0.47) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL17678877 | 0.91 | ALDH1A1 (0.54) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL19307997 | 0.87 | ACHE (0.42) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL29457161 | 0.83 | CYP3A4 (0.37) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL24524178 | 0.81 | ALDH1A1 (0.64) | CYP3A4CASP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL17789217 | 0.78 | ACHE (0.46) | CYP3A4CASP1RECQLALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751985-B2 | Triptycene-based dianhydrides, polyimides, methods of making each, and methods of use | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2017-09-05 | — | — | US | disclosed |
| US-20160367948-A1 | CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES | KYOTO UNIVERSITY (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20160367948-A1 | CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES | KYOTO UNIVERSITY (JP) | 2016-12-22 | — | — | US | disclosed |
| US-9458376-B2 | Electrochromic iptycenes | POLISHAK BRENT M (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458376-B2 | Electrochromic iptycenes | POLISHAK BRENT M (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160137914-A1 | ELECTROCHROMIC IPTYCENES | POLISHAK BRENT M (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160137914-A1 | ELECTROCHROMIC IPTYCENES | POLISHAK BRENT M (US) | 2016-05-19 | — | — | US | disclosed |
| US-9018270-B2 | Method for producing polymers comprising multiple repeat units of bicyclic diamines | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2015-04-28 | — | — | US | disclosed |
| US-9018270-B2 | Method for producing polymers comprising multiple repeat units of bicyclic diamines | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2015-04-28 | — | — | US | disclosed |
| US-20130267616-A1 | Polymerisation Method | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| US-20130267616-A1 | Polymerisation Method | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| WO-2012035327-A1 | POLYMERISATION METHOD | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137914-A1 | ELECTROCHROMIC IPTYCENES | IDH3A, EYA2, IDH2 | CYP3A4 1929/4885CASP1 4447/4885RECQL 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.