Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617245 | 1.00 | PTGES (0.43) | PTGESLMNAERCC1ERCC4ALDH1A1 | |
| SCHEMBL13201540 | 0.81 | NPSR1 (0.42) | LMNAALDH1A1HTTKMT2AL3MBTL1 | |
| SCHEMBL12436040 | 0.80 | MAPKAPK2 (0.31) | — | |
| SCHEMBL21256180 | 0.80 | MAPKAPK2 (0.43) | PTGESLMNAERCC1ERCC4ALDH1A1 | |
| SCHEMBL19652463 | 0.78 | CYP1A2 (0.38) | LMNAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL29561964 | 0.78 | CYP1A2 (0.38) | LMNAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13218642 | 0.77 | HPGD (0.33) | LMNAALDH1A1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL23042833 | 0.77 | L3MBTL1 (0.33) | LMNAALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL1128663 | 0.77 | KMT2A (0.32) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12436062 | 0.77 | PTGES (0.40) | PTGESALDH1A1KDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994167-A | Imidazo [1,5-a ] pyrazine antitumor compound and preparation method and application thereof | 南京健康产业研究院 | 2024-11-22 | — | — | CN | disclosed |
| CN-114621233-A | Substituted aromatic condensed ring derivative and its composition and use | 深圳市塔吉瑞生物医药有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112552302-B | Substituted aromatic fused ring derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |