SCHEMBL29636352

SCHEMBL29636352

CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](C)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 1/20 0.42
FURIN P09958 5/20 0.41
NPY4R P50391 11/20 0.40
NPY1R P25929 7/20 0.40
NPY2R P49146 5/20 0.40
NPY5R Q15761 5/20 0.40
SIRT2 Q8IXJ6 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
NMT2 O60551 1/20 0.38
NMT1 P30419 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636360 0.98 FURIN (0.41) NOD1FURINNPY4RNPY1RNPY2R
SCHEMBL29870738 0.93 NOD1 (0.46) NOD1FURINNPY4RNPY1RNPY2R
SCHEMBL29636351 0.93 NPY4R (0.44) FURINNPY4RNPY1RNPY2RNPY5R
SCHEMBL3074247 0.93 NPY4R (0.48) NOD1FURINNPY4RNPY1RNPY2R
SCHEMBL29636356 0.93 NPY4R (0.48) NOD1FURINNPY4RNPY1RNPY2R
SCHEMBL3074240 0.93 NPY4R (0.48) NOD1FURINNPY4RNPY1RNPY2R
SCHEMBL29636367 0.90 NPY4R (0.48) FURINNPY4RNPY1RNPY2RNPY5R
SCHEMBL29636369 0.90 NPY4R (0.44) FURINNPY4RNPY1RNPY2RNPY5R
SCHEMBL20439405 0.90 SIRT5 (0.43) FURINNPY4RNPY1RNPY2RNPY5R
SCHEMBL16189773 0.90 SIRT5 (0.43) FURINNPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3187508-B1 LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF BIOMARIN PHARM INC (US) 2026-04-22 EP disclosed
US-20230241187-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2023-08-03 US disclosed
US-20220354934-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2022-11-10 US disclosed
US-11351231-B2 Lysosomal targeting peptides and uses thereof BIOMARIN PHARMACEUTICAL INC. (US) 2022-06-07 US disclosed