SCHEMBL29636455

SCHEMBL29636455

COc1ccc2c(c1)Sc1cc(OC)ccc1N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 9/20 1.00
NOX1 Q9Y5S8 6/20 0.83
MAPT P10636 4/20 0.83
GAA P10253 3/20 0.83
KMT2A Q03164 3/20 0.83
MAPK1 P28482 2/20 0.83
MEN1 O00255 2/20 0.83
TDP1 Q9NUW8 2/20 0.83
LMNA P02545 1/20 0.83
HTT P42858 1/20 0.83
SMN1; SMN2 Q16637 1/20 0.83
L3MBTL1 Q9Y468 1/20 0.83
MAOA P21397 2/20 0.59
MAOB P27338 1/20 0.59
ALDH1A1 P00352 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 2/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3489840 1.00 SNCA (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL4080414 0.91 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL17289246 0.91 SNCA (0.83) SNCANOX1MAPTGAAKMT2A
SCHEMBL7664911 0.89 SNCA (0.80) SNCANOX1MAPTGAAKMT2A
SCHEMBL12311067 0.85 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL7673272 0.85 SNCA (0.73) SNCANOX1MAPTGAAKMT2A
SCHEMBL9813306 0.84 SNCA (0.71) SNCANOX1MAPTGAAKMT2A
SCHEMBL17999665 0.83 SNCA (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL239600 0.80 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A
Phenothiazine SCHEMBL9074312 0.80 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271309-A Electrochromic compound, preparation method thereof, electrochromic composition, electrochromic device and electronic equipment 比亚迪股份有限公司 2024-07-02 CN disclosed
EP-4237498-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS Milliken & Company (US) 2023-09-06 EP disclosed
WO-2022093189-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY (US) 2022-05-05 WO disclosed