SCHEMBL3489840

SCHEMBL3489840

COc1ccc2c(c1)Sc1cc(OC)ccc1N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 9/20 1.00
NOX1 Q9Y5S8 6/20 0.83
MAPT P10636 4/20 0.83
GAA P10253 3/20 0.83
KMT2A Q03164 3/20 0.83
MAPK1 P28482 2/20 0.83
MEN1 O00255 2/20 0.83
TDP1 Q9NUW8 2/20 0.83
LMNA P02545 1/20 0.83
HTT P42858 1/20 0.83
SMN1; SMN2 Q16637 1/20 0.83
L3MBTL1 Q9Y468 1/20 0.83
MAOA P21397 2/20 0.59
MAOB P27338 1/20 0.59
ALDH1A1 P00352 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 2/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636455 1.00 SNCA (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL4080414 0.91 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL17289246 0.91 SNCA (0.83) SNCANOX1MAPTGAAKMT2A
SCHEMBL7664911 0.89 SNCA (0.80) SNCANOX1MAPTGAAKMT2A
SCHEMBL12311067 0.85 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL7673272 0.85 SNCA (0.73) SNCANOX1MAPTGAAKMT2A
SCHEMBL9813306 0.84 SNCA (0.71) SNCANOX1MAPTGAAKMT2A
SCHEMBL17999665 0.83 SNCA (1.00) SNCANOX1MAPTGAAKMT2A
SCHEMBL239600 0.80 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A
Phenothiazine SCHEMBL9074312 0.80 NOX1 (1.00) SNCANOX1MAPTGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US claimed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US claimed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP claimed
CN-112513238-A Stable compositions comprising leuco compounds 美利肯公司 2021-03-16 CN claimed
WO-2020023812-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2020-01-30 WO claimed
US-20200032173-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2020-01-30 US claimed
US-20200032167-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY 2020-01-30 US claimed
US-20180057471-A1 Two-Electron Donating Phenothiazines and Use Thereof UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2018-03-01 US claimed
EP-4543863-A1 FERROPTOSIS INHIBITORS AND USES THEREOF University Of Ottawa (CA) 2025-04-30 EP disclosed
CN-118271309-A Electrochromic compound, preparation method thereof, electrochromic composition, electrochromic device and electronic equipment 比亚迪股份有限公司 2024-07-02 CN disclosed
WO-2023245297-A1 FERROPTOSIS INHIBITORS AND USES THEREOF UNIVERSITY OF OTTAWA (CA) 2023-12-28 WO disclosed
US-20230392018-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY 2023-12-07 US disclosed
EP-4237498-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS Milliken & Company (US) 2023-09-06 EP disclosed
WO-2022093189-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY (US) 2022-05-05 WO disclosed
US-5756356-A COLORIMETRIC TOYO INK MANUFACTURING CO., LTD. (JP) 1998-05-26 US disclosed
EP-0735368-A1 Method of indicating time or temperature-time accumulated value as color change, and materials therefor TOYO INK MANUFACTURING CO., LTD. (JP) 1996-10-02 EP disclosed
CN-1086825-A Three ring and tetracyclic compounds HOFFMANN LA ROCHE (CH) 1994-05-18 CN disclosed
EP-0592791-A2 Tricyclic compounds and peptide derivatives thereof F. HOFFMANN-LA ROCHE AG (CH) 1994-04-20 EP disclosed
US-4719174-A USING ABSORPTIVE COMPOUND WHICH RELEASES ELECTRONS UPON EXPOSURE FUJI PHOTO FILM CO., LTD. (JP) 1988-01-12 US disclosed
US-4607006-A Silver halide photographic light-sensitive material containing non-spectral sensitizing electron donative silver halide adsorptive compound FUJI PHOTO FILM CO., LTD. (JP) 1986-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057471-A1 Two-Electron Donating Phenothiazines and Use Thereof SLC6A12, SLCO1B3, SLCO1A2 SNCA 1505/4885NOX1 3353/4885MAPT 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.