Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | DRD1 | P21728 | 2/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 1.00 |
| ▸ | DRD5 | P21918 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | GFER | P55789 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL40951 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL28324791 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL27754471 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL3954271 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL28285902 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL23704750 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29831984 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL40952 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL30379446 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29201795 | 0.98 | KDM4E (0.96) | KDM4EMAPTLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119752337-A | Protective adhesive tape for power battery shell and preparation method thereof | 湖南上晟新材料科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119349944-B | High-strength water permeable brick and preparation method thereof | 永州湘祁水泥制品有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119349944-A | High-strength water permeable brick and preparation method thereof | 永州湘祁水泥制品有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-118970361-A | Preparation method of modified coating of lithium ion battery diaphragm | 南通大学 | 2024-11-15 | — | — | CN | claimed |
| CN-113667188-B | Modified mullite, water-based intumescent fire retardant coating and preparation method thereof | 武汉工程大学 | 2022-09-30 | — | — | CN | claimed |
| CN-114899370-A | Carbon-coated lithium ion battery positive electrode material and preparation method thereof | 山东精工电子科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114574026-A | Modified zeolite and water-based intumescent fire-retardant coating based on modified zeolite | 武汉工程大学 | 2022-06-03 | — | — | CN | claimed |
| CN-120142194-A | Optical fiber sensor for detecting drug concentration and drug concentration detection system | 西安交通大学医学院第一附属医院 | 2025-06-13 | — | — | CN | disclosed |
| CN-119752337-A | Protective adhesive tape for power battery shell and preparation method thereof | 湖南上晟新材料科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119349944-B | High-strength water permeable brick and preparation method thereof | 永州湘祁水泥制品有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119349944-B | High-strength water permeable brick and preparation method thereof | 永州湘祁水泥制品有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119349944-A | High-strength water permeable brick and preparation method thereof | 永州湘祁水泥制品有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119349944-A | High-strength water permeable brick and preparation method thereof | 永州湘祁水泥制品有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-115926286-B | Composite flame-retardant polymer material and preparation method thereof | 浙江昕宇新材料有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115926286-A | Composite flame-retardant high polymer material and preparation method thereof | 浙江昕宇新材料有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113667188-B | Modified mullite, water-based intumescent fire retardant coating and preparation method thereof | 武汉工程大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-114899370-A | Carbon-coated lithium ion battery positive electrode material and preparation method thereof | 山东精工电子科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-113437277-B | Bi 2 S 3 /NiS 2 @ C negative electrode material, sodium ion battery and preparation method of sodium ion battery | 广东工业大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114574026-A | Modified zeolite and water-based intumescent fire-retardant coating based on modified zeolite | 武汉工程大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-114574026-A | Modified zeolite and water-based intumescent fire-retardant coating based on modified zeolite | 武汉工程大学 | 2022-06-03 | — | — | CN | disclosed |