Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | DRD1 | P21728 | 2/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 1.00 |
| ▸ | DRD5 | P21918 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | GFER | P55789 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL28324791 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29636832 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL27754471 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL3954271 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL28285902 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL23704750 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29831984 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL40952 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL30379446 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29201795 | 0.98 | KDM4E (0.96) | KDM4EMAPTLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 37068 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260145158-A1 | APPLICATION OF CARBOXYLATED COVALENT ORGANIC MAGNETIC FRAMEWORK MATERIAL AS MAGNETIC SOLID-PHASE EXTRACTION ADSORBENT | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-28 | — | — | US | claimed |
| US-20260146183-A1 | SUPRAMOLECULAR HYDROGEL FILM FOR REVERSIBLE ADHESION OF FROZEN FOOD, PRODUCTION METHOD, AND APPLICATION | NANJING AGRICULTURAL UNIVERSITY (CN) | 2026-05-28 | — | — | US | claimed |
| CN-122075805-A | Anticoagulation anti-infection dialysis catheter coating and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-120249726-B | Preparation method of high-tungsten alloy oil sleeve | SHENGLI OILFIELD JINDAO INDUSTRIAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122081017-A | Mite-removing sulfur liquid soap and processing technology thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094536-A | Low-loss high-frequency carrier plate and manufacturing method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079714-A | Composite solid propellant and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121516937-B | Long-acting controlled-release antibacterial deodorizing material for water treatment and preparation method thereof | Xi'an Water Innovation Material Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080912-A | Emulsion type intelligent fracturing fluid for high-diversion channel and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-120818189-B | Preparation method of high-performance regenerated rubber based on modified calcium sulfate whisker and rice hull carbon | QIQIHAR UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-1134159-A | Cysteine-free metal-binding peptides for diagnostic and therapeutic purposes, method for the production thereof and medicaments containing these compounds | DIAGNOSTIKFORSCHUNG INST (DE) | 1996-10-23 | — | — | CN | claimed |
| CN-1124489-A | Tetracyclic compounds as dopamine agonists | ABBOTT LAB (US) | 1996-06-12 | — | — | CN | claimed |
| CN-1092468-A | The authentication method of cryptococcus neoformans and used substratum thereof | INST OF DERMATOSIS CHINESE ACA (CN) | 1994-09-21 | — | — | CN | claimed |
| US-5288503-A | WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL | SRCHEM INCORPORATED (US) | 1994-02-22 | — | — | US | claimed |
| US-5260066-A | Cryogel bandage containing therapeutic agent | SRCHEM INCORPORATED (US) | 1993-11-09 | — | — | US | claimed |
| CN-1044652-A | Pyrrolidine compound and its pharmaceutical use | EISAI CO LTD (JP) | 1990-08-15 | — | — | CN | claimed |
| CN-87103323-A | The method for preparing new Dopamine HCL, hydroxylase inhibitors | — | 1988-02-03 | — | — | CN | claimed |
| CN-85104166-A | Preparation of new medicine and its preparation | — | 1986-11-26 | — | — | CN | claimed |
| US-4423139-A | SYNERGISTIC MIXTURE OF AROMATIC POLYOL, AROMATIC DIAMINE, OR AROMATIC OXYAMINE WITH 1-PHENYL-3-PYRAZOLIDINONE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-12-27 | — | — | US | claimed |
| US-4379835-A | Black image from a thermographic imaging system | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-04-12 | — | — | US | claimed |