Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | DRD1 | P21728 | 2/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 1.00 |
| ▸ | DRD5 | P21918 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | GFER | P55789 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL40951 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL28324791 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29636832 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL27754471 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL3954271 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL28285902 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL23704750 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29831984 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL30379446 | 1.00 | KDM4E (1.00) | KDM4EMAPTLMNAMAPK1TDP1 | |
| Dopamine SCHEMBL29201795 | 0.98 | KDM4E (0.96) | KDM4EMAPTLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 30833 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146183-A1 | SUPRAMOLECULAR HYDROGEL FILM FOR REVERSIBLE ADHESION OF FROZEN FOOD, PRODUCTION METHOD, AND APPLICATION | NANJING AGRICULTURAL UNIVERSITY (CN) | 2026-05-28 | — | — | US | claimed |
| US-20260145158-A1 | APPLICATION OF CARBOXYLATED COVALENT ORGANIC MAGNETIC FRAMEWORK MATERIAL AS MAGNETIC SOLID-PHASE EXTRACTION ADSORBENT | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-28 | — | — | US | claimed |
| CN-122075723-A | Application of Lamp2b-IMTP fusion exosome in treating coronary heart disease | — | 2026-05-26 | — | — | CN | claimed |
| CN-122091807-A | Metal organic framework coated lithium supplementing agent and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-120464197-B | Polyimide film and preparation method and application thereof | Jiaxing Nanbo Precision Manufacturing Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-117643648-B | Injectable self-healing hydrogel dressing and preparation method and application thereof | SICHUAN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080727-A | 8B cold-rolled precise steel strip and manufacturing method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-120324686-B | GTR film and preparation method and application thereof | SICHUAN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122076677-A | Antibacterial composite coating based on quaternized nano zinc oxide and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080742-A | Ultralow-VOC (volatile organic compound) graphene anti-corrosion curing coating and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| WO-2001037808-A1 | SOLID CARRIERS FOR IMPROVED DELIVERY OF ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS | LIPOCINE, INC. (US) | 2001-05-31 | — | — | WO | claimed |
| WO-2001028555-A1 | EMULSION COMPOSITIONS FOR POLYFUNCTIONAL ACTIVE INGREDIENTS | LIPOCINE, INC. (US) | 2001-04-26 | — | — | WO | claimed |
| WO-2001012155-A1 | COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS | LIPOCINE, INC. (US) | 2001-02-22 | — | — | WO | claimed |
| WO-2000021504-A1 | ENCAPSULATION OF SENSITIVE LIQUID COMPONENTS INTO A MATRIX TO OBTAIN DISCRETE SHELF-STABLE PARTICLES | GENERAL MILLS, INC. (US) | 2000-04-20 | — | — | WO | claimed |
| EP-0935523-A4 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GEN MILLS INC (US) | 1999-12-29 | — | — | EP | claimed |
| EP-0935523-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GENERAL MILLS, INC. (US) | 1999-08-18 | — | — | EP | claimed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| WO-1998018610-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | LENGERICH BERNHARD H VAN (US) | 1998-05-07 | — | — | WO | claimed |
| US-5288503-A | WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL | SRCHEM INCORPORATED (US) | 1994-02-22 | — | — | US | claimed |
| US-5260066-A | Cryogel bandage containing therapeutic agent | SRCHEM INCORPORATED (US) | 1993-11-09 | — | — | US | claimed |