Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23406402 | 1.00 | ALDH1A1 (0.77) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL20357282 | 0.88 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL9424069 | 0.87 | LMNA (0.71) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL1813423 | 0.87 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL1806134 | 0.84 | SMN1; SMN2 (0.80) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL1811373 | 0.84 | ALDH1A1 (0.83) | ALDH1A1L3MBTL1GAASMN1; SMN2TSHR | |
| SCHEMBL27073133 | 0.84 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL12653715 | 0.83 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL13540499 | 0.82 | SRPK1 (0.79) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL1815374 | 0.82 | SMN1; SMN2 (0.80) | ALDH1A1L3MBTL1GAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240408105-A1 | USE OF SMALL MOLECULE FAK ACTIVATORS TO PROMOTE MUCOSAL HEALING | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2024-12-12 | — | — | US | disclosed |
| EP-4232016-A1 | USE OF SMALL MOLECULE FAK ACTIVATORS TO PROMOTE MUCOSAL HEALING | University Of North Dakota (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022093780-A1 | USE OF SMALL MOLECULE FAK ACTIVATORS TO PROMOTE MUCOSAL HEALING | UNIVERSITY OF NORTH DAKOTA (US) | 2022-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240408105-A1 | USE OF SMALL MOLECULE FAK ACTIVATORS TO PROMOTE MUCOSAL HEALING | PTK2, CTTN, TNK2 | ALDH1A1 3500/4885L3MBTL1 3515/4885GAA 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.