Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1186674 | 0.88 | GLO1 (0.67) | GLO1GAANPSR1ALDH1A1CYP2D6 | |
| SCHEMBL4197379 | 0.88 | GLO1 (0.67) | GLO1GAANPSR1ALDH1A1CYP2D6 | |
| SCHEMBL1186672 | 0.88 | GLO1 (0.67) | GLO1GAANPSR1ALDH1A1CYP2D6 | |
| SCHEMBL18329297 | 0.81 | GAA (0.48) | GLO1GAAMGAMSIMGAM2 | |
| SCHEMBL50838 | 0.78 | NPSR1 (0.56) | GLO1GAAMGAMSIMGAM2 | |
| SCHEMBL24937270 | 0.78 | GLO1 (0.57) | GLO1GAANPSR1ALDH1A1CYP2D6 | |
| SCHEMBL28786257 | 0.78 | GLO1 (0.57) | GLO1GAANPSR1ALDH1A1CYP2D6 | |
| SCHEMBL11650327 | 0.77 | GLO1 (0.45) | GLO1GAAMGAMSIMGAM2 | |
| SCHEMBL11650330 | 0.77 | GLO1 (0.45) | GLO1GAAMGAMSIMGAM2 | |
| SCHEMBL15500 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228632-A2 | REV-ERB AGONISTS | Saint Louis University (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022093552-A2 | REV-ERB AGONISTS | Saint Louis Univeristy (US) | 2022-05-05 | — | — | WO | disclosed |