Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071501 | 0.74 | TYMP (0.74) | TYMP | |
| Hydrochloric Acid SCHEMBL29636873 | 0.73 | TYMP (0.74) | TYMP | |
| Tipiracil SCHEMBL1682960 | 0.72 | TYMP (1.00) | TYMP | |
| Tipiracil SCHEMBL1682924 | 0.71 | TYMP (1.00) | TYMP | |
| SCHEMBL10054274 | 0.70 | TYMP (0.67) | TYMP | |
| SCHEMBL1682985 | 0.68 | TYMP (0.63) | TYMP | |
| SCHEMBL1682926 | 0.68 | TYMP (0.59) | TYMP | |
| SCHEMBL1682928 | 0.67 | TYMP (0.62) | TYMP | |
| Bromide SCHEMBL20184792 | 0.65 | L3MBTL1 (0.53) | — | |
| SCHEMBL809810 | 0.64 | INMT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203437-B | Preparation method and application of two kinds of tipiracil impurities | 海南先声药业有限公司 | 2022-05-13 | — | — | CN | disclosed |