SCHEMBL29637424

SCHEMBL29637424

Nc1ccc(-c2ccccc2-c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
PTPRC P08575 2/20 0.57
NCOA1 Q15788 2/20 0.57
LMNA P02545 2/20 0.57
HPGD P15428 2/20 0.57
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
APAF1 O14727 1/20 0.57
TDP2 O95551 1/20 0.57
NSD2 O96028 1/20 0.57
PLA2G1B P04054 1/20 0.57
POLB P06746 1/20 0.57
CTSL P07711 1/20 0.57
ALOX12 P18054 1/20 0.57
PLCG1 P19174 1/20 0.57
CTSS P25774 1/20 0.57
NPY1R P25929 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30545213 1.00 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL4395100 1.00 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL16820312 0.95 PTPRC (0.63) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL38924 0.95 ALDH1A1 (0.56) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL4454543 0.95 CYP3A4 (0.52) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL30108087 0.95 ALDH1A1 (0.56) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL1099351 0.92 MAOA (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL2989031 0.92 MAOA (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL29634747 0.91 PTPRC (0.59) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC
SCHEMBL12478792 0.91 CYP3A4 (0.50) ALDH1A1NPC1RAB9ASMN1; SMN2PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116210359-A Organic electroluminescent element 保土谷化学工业株式会社 2023-06-02 CN disclosed
CN-114586189-A Organic electroluminescent element 保土谷化学工业株式会社 2022-06-03 CN disclosed