SCHEMBL29637482

SCHEMBL29637482

Cc1cc(Br)c(Br)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 6/20 0.42
LMNA P02545 1/20 0.39
AHR P35869 1/20 0.39
KDM1A O60341 2/20 0.34
KDM1B Q8NB78 1/20 0.34
APEX1 P27695 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NQO2 P16083 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1135594 1.00 TSHR (0.44) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL11045804 0.85 ALDH1A1 (0.38) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL29366549 0.85 TSHR (0.47) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL133345 0.85 TSHR (0.47) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL120851 0.83 ALDH1A1 (0.42) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL2347027 0.82 TSHR (0.38) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL17298241 0.79 CYP3A4 (0.58) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL12403114 0.79 TSHR (0.37) TSHRCYP3A4MAPK1ALDH1A1LMNA
SCHEMBL23230056 0.77 ALOX15 (0.50) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL21202945 0.77 TSHR (0.35) TSHRCYP3A4MAPK1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929907-B Polyimide precursor, polyimide precursor composition, polyimide film, preparation method and application thereof SK新技术株式会社 2025-05-13 CN disclosed
CN-113195801-B Crystal, method for producing crystal, and method for self-assembling silanol compound 国立研究开发法人产业技术综合研究所 2024-10-15 CN disclosed
CN-114213441-B Boron or phosphorus fused ring compound, preparation method thereof and light-emitting device 中国科学院长春应用化学研究所 2023-12-01 CN disclosed
CN-111689995-B High-solubility triaryl carbon borate and preparation method and application thereof 万华化学集团股份有限公司 2023-09-19 CN disclosed
CN-114933668-B Oxygen-containing cycloolefin addition polymer and preparation method thereof 万华化学集团股份有限公司 2023-07-14 CN disclosed
CN-115433227-A Multidentate phosphine coordinated copper trihalo tri-type complex, and synthesis method and application thereof 黑龙江大学 2022-12-06 CN disclosed
CN-114933668-A Oxygen-containing cycloolefine addition polymer and its preparation method 万华化学集团股份有限公司 2022-08-23 CN disclosed
CN-114585627-A Molecular materials based on phenoxyazine cores for heterojunction organic solar cells 住友化学株式会社 2022-06-03 CN disclosed
CN-114213441-A Boron-doped or phosphorus-doped fused ring compound, preparation method thereof and light-emitting device 中国科学院长春应用化学研究所 2022-03-22 CN disclosed